Juventus failed to end Parma’s unbeaten home record, as Nicola Sansone cancelled out an Andrea Pirlo free kick.
The Bianconeri suffered a shock home defeat to 10-man Sampdoria last week and were pushed to extra time in the Coppa Italia by Milan on Wednesday, so they were far from confident going to face the only team with an unbeaten home record this season.
Claudio Marchisio, Giorgio Chiellini, Nicklas Bendtner and Simone Pepe were out injured, Kwadwo Asamoah on African Cup of Nations duty, while Parma had Alessandro Lucarelli and Yohan Benalouane banned.
Amauri and Sebastian Giovinco started against their former clubs. Gabriel Paletta fired over early on from a poor clearance, as did Massimo Gobbi after a give-and-go with Amauri.
Gigi Buffon parried an Ishak Belfodil attempt and the French talent curled another effort just off target, as Parma dominated the early stages.
Paul Pogba’s strike was wide from distance, but it was all Parma, as Belfodil’s shot on the counter was charged down in the box and Amauri turned the rebound over.
Stephan Lichtsteiner went close at the other end, but his effort was deflected out for a corner at the near post. From that poorly-cleared set piece Antonio Mirante came sprinting out to clear from Fabio Quagliarella.
Parma went straight on the counter and Buffon made a hash of punching away the ball, eventually scrambling clear.
Mirante flew to fingertip a classic Andrea Pirlo free kick out from under the crossbar.
Juventus took the lead after the restart when another Pirlo free kick took a huge deflection off Jonathan Biabiany in the wall to completely wrong-foot Mirante.
Quagliarella attempted a lob from midfield, but it was just over the bar. However, Juve were caught out with a classic counter-attack when Gabriel Paletta intercepted a Mirko Vucinic dummy in midfield.
Nicola Sansone used his pace to burst past Martin Caceres and kept his cool for an angled drive across Buffon.
Vucinic tried to make up for it with an angled drive that bounced in front of Mirante, but the goalkeeper got it under control. Belfodil nodded over his own goal, while at the other end the same player came sliding in and just failed to redirect a wayward Afriyie Acquah strike.