Lazio had the best scoring opportunities with Hernanes and Brayan Perea, but were held to a 0-0 draw by Fiorentina.
This was a head-to-head for European qualification and both were fresh from dramatic continental trips on Thursday. The Biancocelesti drew 3-3 at Trabzonspor and gave Felipe Anderson and Brayan Perea their full Serie A debuts, as Miroslav Klose, Abdoulay Konko, Giuseppe Biava, Stefan Radu, Bruno Pereirinha and the suspended Stefano Mauri missed out. The Viola won 2-1 with Dnipro and welcomed back Giuseppe Rossi from a muscular problem, though Mario Gomez and Ante Rebic were still out.
Pepito was in the mood to celebrate, as before kick-off he received word he had been called for Italy after a two-year injury hiatus.
Lazio wore special jerseys and black socks commemorating all-time Serie A top scorer Silvio Piola, as September 29 was the 100th anniversary of his birth.
Fiorentina kept much of the early possession, but Brayan Perea dispossessed David Pizarro and dummied Stefan Savic only to drill inches past the far post.
Hernanes forced a tough save out of Neto with his powerful angled drive and a free kick skimmed the woodwork.
Michael Ciani nodded over from a corner and Hernanes blasted off target after some wonderful one-touch football involving Antonio Candreva, Felipe Anderson and Perea.
After the restart Manuel Pasqual’s free kick dipped over the bar and Perea’s header went the same way on a Senad Lulic cross.
Marchetti got down well to beat away a dangerous Rossi free kick at the near post, which had also skimmed the head of Savic.
Sergio Floccari came off the bench and Neto needed a touch to turn his angled drive off target, then Gonzalo Rodriguez dived in for a decisive block on Lulic as he was pulling the trigger.
Neto parried another Hernanes snapshot and did well to smother a deflected Candreva free kick. One of Candreva’s trademark rockets from distance whizzed inches past the near top corner and a deflection turned Floccari’s attempt wide from four yards set up by Hernanes.
The fatigue from Thursday’s Europa League games took its toll on both teams, as the tempo dropped considerably in the second half.