Second from bottom Cesena take on third from bottom Cagliari in this match between two relegated sides.
Chievo and Atalanta can play free of pressure after securing their Serie A safety for another season.
Sampdoria need a victory to get back into the Europa League positions, but visit an Empoli side eager to end on a high.
It’s all or nothing for Napoli as their pursuit of Champions League qualification comes to a head at Serie A champions Juventus.
It’s a Champions League qualification play-off, as Lazio and Roma gear up for a derby with European significance.
Milan welcome Torino on Sunday in a game between two teams whose histories are more intertwined than one would think, and whose roles have been reversed of late.
Fiorentina travel to Sicily Sunday afternoon aiming to cement their European place against a Palermo side playing purely for pride.
Luca Toni will look to add to his impressive goalscoring haul as Verona visit relegated Parma at the Stadio Ennio Tardini.
Following a morale-boosting win over AC Milan, Sassuolo will be hoping to make it three wins on the trot as they travel to face Udinese, who are seeking to avoid a third straight loss.