Lazio will be without Albanian midfielder Lorik Cana for Friday's clash against Milan after he picked up an injury in training.
The summer signing limped off during yesterday's session and has now been diagnosed with a first degree right thigh strain.
“Therefore the athlete will not be available for Friday evening's game in Milan,” read a note on the official club website.
Lazio are also without Stefan Radu because of a knee inflammation and the suspended Federico Marchetti.
There are fitness doubts over Giuseppe Sculli, Guglielmo Stendardo, Libor Kozak and Marius Stankevicius.