Milos Krasic starts with Alessandro Del Piero and Mirko Vucinic for Juventus, but Bologna drop Marco Di Vaio.
Antonio Conte sticks by his 4-2-4 system with Andrea Pirlo and Claudio Marchisio the midfield enforcers.
There is a new quartet in attack, as Milos Krasic receives his first start of the season, joining Vucinic, Del Piero and Simone Pepe.
Paolo De Ceglie returns from suspension to take the left-back role.
Bologna are in dire straits without a single point or goal so far this season, but have chosen to remarkably drop Marco Di Vaio.
It is not yet clear if there are fitness reasons behind this shock decision, but Robert Acquafresca leads the attack with Gaston Ramirez and Panagiotis Kone'.
Juventus: Buffon; Lichtsteiner, Barzagli, Chiellini, De Ceglie; Marchisio, Pirlo; Krasic, Vucinic, Del Piero, Pepe
Juventus bench: Storari, Bonucci, Vidal, Elia, Giaccherini, Matri, Quagliarella
Bologna: Gillet; Casarini, Portanova, Antonsson, Morleo; Diamanti, Perez, Mudingayi, Kone; Ramirez; Acquafresca
Bologna bench: Agliardi, Crespo, Rickler, Pulzetti, Khrin, Paponi, Di Vaio
Think you know your Italian football? Share your knowledge, tips and comments to win cash prizes in OLBG's tipster competition - £11,000 to be won monthly!