Udinese have constructed an all-new front pairing of Almen Abdi and Diego Fabbrini against Celtic in the Europa League.
The match kicks off at Celtic Park at 18.00 UK time and the Friulani hope to build on their opening 2-1 win over Rennes.
Francesco Guidolin has left behind many of his star names for this trip to Scotland, including Antonio Di Natale, Maurizio Domizzi and the injured Vitor Paulo Barreto and Antonio Floro Flores.
The Coach opted for an all-new front pairing of Abdi and Under-21 international playmaker Fabbrini, neither of whom are centre-forwards. Full-back Neuton is moved into wide midfield.
Others rested on the bench include Mauricio Isla, Kwadwo Asamoah, Giampiero Pinzi, Mehdi Benatia and Pablo Armero, though 19-year-old Argentine Christian Battocchio starts in midfield.
Celtic are without Kris Commons, Badr El-Kaddouri, Emilio Izaguirre, Kelvin Wilson, Cha Du-ri and Scott Brown, but Gary Hooper is ready to start despite an ankle problem.
Mo Bangura is given his first start for the Scots and Victor Wanyama replaces Glenn Loovens, while Charlie Mulgrew is back from suspension.
The Hoops lost their first Group I game 2-0 at Atletico Madrid.
Celtic: Zaluska; Matthews, Majstorovic, Wanyama, Mulgrew; Forrest, Ki Sung-Yong, Kayal, Ledley; Bangura, Hooper
Celtic bench: Forster, M Wilson, Loovens, F Twardzik, McCourt, Samaras, Stokes
Udinese: Handanovic; Basta, Danilo, Ekstrand; Pereyra, Doubai, Battocchio, Badu, Neuton; Abdi; Fabbrini
Udinese bench: Padelli, Benatia, Armero, Isla, Asamoah, Pinzi, Marsura