Edinson Cavani has not made it into the Napoli squad travelling to San Siro for tomorrow's game against Inter.
The striker sprained his ankle during the 2-0 Champions League victory over Villarreal and had been initially ruled out for a week.
That was reduced following treatment and he took part in training with some light running on Thursday, fuelling speculation he'd make a last-gasp recovery.
However, Coach Walter Mazzarri unveiled his squad list this afternoon and Cavani has been left at home.
Salvatore Aronica was also an injury doubt, but he is in the Napoli side.
Napoli squad: De Sanctis, Rosati, Colombo, Aronica, Campagnaro, Cannavaro, Grava, Fernandez, Fideleff, Dossena, Gargano, Hamsik, Inler, Maggio, Zuniga, Chavez, Lavezzi, Mascara, Pandev, Santana
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