Francesco Totti and Jose Angel are dropped in favour of Erik Lamela and Rodrigo Taddei in tonight’s Roma-Lecce.
Serie A Week 12 concludes with the 19.45 UK time kick-off at the Stadio Olimpico.
Totti returns to the squad after a month out with a thigh strain, but is only on the bench along with Jose Angel.
Instead, Coach Luis Enrique has chosen Lamela and gives Taddei a rare start in a full-back position.
Fabio Borini, David Pizarro and Nicolas Burdisso are unavailable due to injury.
Lecce make the trip without the suspended Luis Muriel, plus David Di Michele, Guillermo Giacomazzi, Souleymane Diamoutene and Djamel Mesbah.
They have former Roma goalkeeper Julio Sergio and striker Daniele Corvia in the starting XI.
Roma: Stekelenburg; Rosi, Kjaer, Heinze, Taddei; Gago, De Rossi, Pjanic; Bojan, Lamela, Osvaldo
Roma bench: Curci, José Angel, Cassetti, Greco, Perrotta, Totti, Borriello
Lecce: Julio Sergio; Oddo, Carrozzieri, Esposito, Tomovic; Strasser, Grossmuller; Cuadrado, Bertolacci, Olivera; Corvia
Lecce bench:Benassi, Brivio, Piatti, Obodo, Giandonato, Pasquato, Ofere