Udinese rest Antonio Di Natale for their Europa League trip to Rennes, handing the reins to Antonio Floro Flores.
The Friulani are currently joint top of Group I with Atletico Madrid on seven points, but Celtic are hovering just behind on five. Rennes prop up the standings with two points.
Francesco Guidolin’s men are therefore under pressure to deliver in France, but he still rests top scorer Di Natale.
Instead, Floro Flores receives support from Under-21 international Diego Fabbrini with Mauricio Isla and Pablo Armero wide.
Rennes have former Inter man Stephan Dalmat in the trequartista role behind two strikers.
Kick-off is at 18.00 UK time at the Stade de la Route-de-Lorient.
Rennes: Costil; Jebbour, Kana-Biyik, Boye, Mavinga; Tettey, Pajot, Brahimi; Dalmat; Boukari, Hadji
Rennes bench: Diallo, Foulquier, Pitroipa, Feret, Mandjeck, Doumbia, Montano
Udinese: Handanovic; Benatia, Danilo, Ekstrand; Isla, Doubai, Badu, Asamoah, Armero; Fabbrini; Floro Flores
Udinese bench: Padelli, Basta, Neuton, Battocchio, Pereyra, Pinzi, Di Natale