Francesco Totti has been ruled out of Sunday night's clash between Inter and Roma after coming down with flu.
The captain is still in bed with a fever and will not even make the trip up to San Siro.
David Pizarro is also still absent following a long injury lay-off, though Matteo Brighi does recover in time.
Philippe Mexes begins sitting out his two-match ban for insulting the officials in Wednesday night's 1-1 draw with Brescia.
Defender Simone Loria is added to the squad for the first time this season.
Roma squad: Julio Sergio, Borriello, Brighi, G Burdisso, N Burdisso, Cassetti, Castellini, De Rossi, Doni, Greco, Juan, Lobont, Loria, Menez, Perrotta, Riise, Rosi, Simplicio, Taddei, Vucinic