Adrian Mutu, Alberto Gilardino and Valon Behrami welcome Dejan Stankovic, Giampaolo Pazzini and Samuel Eto'o in Fiorentina-Inter.
The rescheduled Serie A game was postponed from December when the Nerazzurri were at the Club World Cup.
It kicks off at 17.30 UK time at the Stadio Artemio Franchi in Florence.
Gilardino is partnered by Mutu and Mario Alberto Santana in a trident attack, with support from January signing Behrami.
Marco Donadel is chosen for the midfield rather than Gaetano D'Agostino, while Lorenzo De Silvestri is also benched.
Leonardo gives Yuto Nagatomo his first start in an Inter jersey, so Javier Zanetti returns to the midfield.
Stankovic makes his comeback from an injury lay-off, joining Wesley Sneijder, Pazzini and Eto'o.
Fiorentina: 84 Boruc; 15 Comotto, 5 Gamberini, 31 Camporese, 23 Pasqual; 18 Montolivo, 4 Donadel, 85 Behrami; 7 Santana, 11 Gilardino, 10 Mutu.
Fiorentina bench: 89 Neto, 9 Babacar, 14 Natali, 21 D'Agostino, 22 Ljajic, 29 De Silvestri, 32 Marchionni
Inter :1 Julio Cesar; 13 Maicon, 15 Ranocchia, 2 Cordoba, 55 Nagatomo; 4 Zanetti, 19 Cambiasso, 5 Stankovic; 10 Sneijder; 7 Pazzini, 9 Eto'o
Inter bench: 12 Castellazzi, 14 Kharja, 17 Mariga, 23 Materazzi, 20 Obi, 27 Pandev, 29 Coutinho