Gianluigi Buffon is out of tonight's Roma-Juventus game with flu, but Jeremy Menez starts for the Giallorossi.
The Bianconeri announced the goalkeeper's absence with a note on their official website, confirming he had been struck down by a bout of flu overnight.
Marco Storari therefore takes the gloves, while Andrea Barzagli and Leonardo Bonucci take centre-back roles with Giorgio Chiellini injured.
Alessandro Del Piero also joined the absentee list with Fabio Quagliarella, Jorge Martinez, Leandro Rinaudo, Paolo De Ceglie, Momo Sissoko, Vincenzo Iaquinta and Armand Traoré.
Gigi Del Neri has transformed his tactics, leaving Luca Toni on the bench in favour of a staggered trident, effectively a 4-5-1.
Alessandro Matri is the only real striker backed on the wings by Milos Krasic and Simone Pepe.
Roma also make changes, as Menez is thrown into the starting XI with Mirko Vucinic and Francesco Totti.
Roma: 32 Doni; 29 N Burdisso, 5 Mexes, 4 Juan, 17 Riise; 7 Pizarro, 16 De Rossi; 94 Menez 20 Perrotta, 9 Vucinic; 10 Totti
Roma bench: 1 Lobont, 77 Cassetti, 87 Rosi, 30 Simplicio, 33 Brighi, 22 Borriello
Juventus: 30 Storari; 43 Sorensen, 19 Bonucci, 15 Barzagli, 6 Grosso; 4 Felipe Melo, 14 Aquilani, 8 Marchisio; 23 Pepe, 27 Krasic; 32 Matri
Juventus bench: 13 Manninger, 2 Motta, 7 Salihamidzic, 38 Libertazzi, 21 Grygera, 20 Toni