Roma reshuffle behind Francesco Totti, but Alexis Sanchez picked up a problem in the warm-up for Udinese.
This is a head-to-head for the Champions League spots at the Stadio Friuli and kicks off at 19.45 UK time.
The Friulani must do without the suspended Gokhan Inler, plus Dusan Basta and Damiano Ferronetti.
There were doubts over the fitness of Sanchez, Antonio Di Natale and Mauricio Isla. They were all originally named in the starting XI, but Sanchez failed a last-minute fitness test and moved to the bench in place of German Denis.
Roma lost their unbeaten Serie A record under Vincenzo Montella when falling 2-0 to Juventus last week.
Jeremy Menez, Julio Sergio and Philippe Mexes are injured, but as always Montella has to drop someone in his front line.
Marco Borriello is again left on the bench in favour of Totti and Mirko Vucinic.
There are changes in the supporting trio, as Simone Perrotta and Rodrigo Taddei are rested in favour of Aleandro Rosi and Matteo Brighi.
Udinese: 1 Handanovic; 17 Benatia, 2 Zapata, 11 Domizzi; 3 Isla, 23 Abdi, 66 Pinzi, 20 Asamoah, 27 Armero; 16 Denis, 10 Di Natale
Udinese bench: Belardi, Coda, Angella, Pasquale, Cuadrado, Sanchez, Corradi
Roma: 32 Doni; 77 Cassetti, 29 N Burdisso, 4 Juan, 17 Riise; 7 Pizarro, 16 De Rossi; 87 Rosi, 33 Brighi, 9 Vucinic; 10 Totti
Roma bench: Lobont, Loria, Caprari, Simplicio, Taddei, Perrotta, Borriello
Think you know your Italian football? Share your knowledge, tips and comments to win cash prizes in OLBG's tipster competition - £11,000 to be won monthly!