Inter have received a boost as veteran defender Walter Samuel is back in training again and has even been included in the 22-man squad to face Schalke.
The Argentina international tore his anterior cruciate ligament earlier this season and needed a surgical reconstruction, which has kept him out for 153 days.
Inter need to bring some experience to their backline after last week's 5-2 defeat to Schalke at San Siro.
Indeed, their chances of qualifying for the Champions League semi-finals are very slim.
Leonardo's side got back to winning ways on Saturday with a 2-0 win at home to Chievo.
It's not thought that Samuel will feature on Wednesday. He wasn't expected back at all this season.