Around 50,000 Palermo fans are expected to flood into the Stadio Olimpico for tonight's Coppa Italia Final against Inter.
The Rosanero have never won this trophy and only reached the Final twice in the 1970s, so it is a huge occasion for them.
Reports suggest around 50,000 supporters are descending on Rome for the match, which kicks off at 20.00 UK time.
Armin Bacinovic and Cesare Bovo are suspended, so Afriyie Acquah and Ezequiel Munoz are expected to step in.
It's a gamble for Coach Delio Rossi to count on youngster Acquah, especially as he was replaced due to a tactical decision just 30 minutes into the Coppa semi-final against Milan.
He should have support from old guard midfielders Giulio Migliaccio and Antonio Nocerino.
Fabrizio Miccoli says this will be his final game for Palermo, but he's likely to only have a minor role, as Javier Pastore, Josip Ilicic and Abel Hernandez are expected to start.
Inter are still struggling with Wesley Sneijder's injury and Andrea Ranocchia suffering from a bout of flu.
Douglas Maicon sits out a ban, so there could be some major reshuffling at the back for Leonardo.
It is reported that Cristian Chivu will take the left-back slot, moving Yuto Nagatomo to the right in place of Maicon, so Marco Materazzi could start at centre-back with Lucio if Ranocchia doesn't recover.
Houssine Kharja has been filling the Sneijder role for some time now behind strikers Samuel Eto'o and Giampaolo Pazzini.