Inter have fielded a solid team for the final game against CSKA Moscow, aware top spot in the Champions League group is secure.
Claudio Ranieri can ill afford another defeat due to sinking morale in the team after their 1-0 home loss to Udinese.
On the other hand, CSKA have a very slim chance of qualifying for the last 16, as they must win at San Siro and hope Lille draw with Trabzonspor.
Wesley Sneijder, Douglas Maicon, Lucio and Julio Cesar are all either injured or rested, while Philippe Coutinho is back as support for Diego Milito. Under-21 international Marco Davide Faraoni starts again in midfield.
The Russians miss Igor Akinfeev, Zoran Tosic, Tomas Necid and Mark Gonzalez, but Sergei Ignashevich returns after spraining his ankle.
Inter: Castellazzi; Nagatomo, Ranocchia, Samuel, Chivu; Faraoni, Zanetti, Cambiasso, Obi; Coutinho; Milito
Inter bench: Orlandoni, Caldirola, Thiago Motta, Alvarez, Crisetig, Pazzini, Zarate
CSKA Moscow: Gabulov; Nababkin, V Berezutski, Ignashevich, A Berezutski; Oliseh, Semberas, Mamaev, Dzagoev; Vagner Love, Doumbia
CSKA bench: Chepchugov, Vasin, Schennikov, Fedotov, Cauna, Aldonin, Rahimic
Betting on Serie A? Bet365 are offering a 100% deposit bonus, up to £200 - find out more