Roma have been dealt a real blow to their preparations for Saturday's clash with Milan as Mirko Vucinic has suffered an injury setback.
The Montenegro international has apparently had a relapse of a muscle problem, which hampered his progress earlier in the season.
La Gazzetta dello Sport understands Vucinic left Roma's training group this morning, signifying that he won't be on pitch at San Siro.
Roma need to beat Milan if they are to go into the winter break with any hope of still being in the title race.
A defeat would leave Claudio Ranieri's side 13 points adrift of the League leaders.