Inter have Diego Milito, Diego Forlan and Wesley Sneijder for tonight’s Last Chance Saloon trip to the Stadio San Paolo.
Claudio Ranieri is thought to be hanging by a thread after losing six of the last seven official games.
He makes this journey without Douglas Maicon, Andrea Ranocchia, Ricky Alvarez, Fredy Guarin and the suspended Luc Castaignos.
Sneijder starts behind Forlan and Milito, as Mauro Zarate is sent to the bench.
Curiously, Marco Davide Faraoni is chosen as a makeshift right-back, as Cristian Chivu has been ruled out by a bout of flu.
Napoli have rediscovered their form recently in both Serie A and the Champions League, finding their enthusiasm along with it.
Marek Hamsik sits out a ban, so Blerim Dzemaili steps in to join Edinson Cavani and Ezequiel Lavezzi.
Inter-owned Goran Pandev is only on the bench along with the fit-again Eduardo Vargas.
The Nerazzurri haven’t won at the San Paolo in Serie A since a 2-0 result on October 18 1997, followed by two points from five visits.
Napoli: 1 De Sanctis; 14 Campagnaro, 28 Cannavaro, 6 Aronica; 11 Maggio, 23 Gargano, 88 Inler, 18 Zuniga; 20 Dzemaili; 22 Lavezzi; 7 Cavani
Napoli bench: 83 Rosati, 2 Grava, 21 Fernandez, 85 Britos, 8 Dossena, 29 Pandev, 16 Vargas
Inter: 1 Julio Cesar; 37 Faraoni, 6 Lucio, 25 Samuel, 55 Nagatomo; 4 Zanetti, 5 Stankovic, 19 Cambiasso; 10 Sneijder; 9 Forlan, 22 Milito
Inter bench: 12 Castellazzi, 2 Cordoba, 17 Palombo, 18 Poli, 20 Obi, 7 Pazzini, 28 Zarate
Think you know your Italian football? Share your knowledge, tips and comments to win cash prizes in OLBG's tipster competition  - £5,000 monthly.