Udinese have Antonio Di Natale against Palermo’s Fabrizio Miccoli, as the Rosanero try to avenge a 7-0 defeat.
This fixture ended with an amazing 7-0 result last season, which prompted Palermo to sack Delio Rossi.
Friulani boss Francesco Guidolin knows the feeling, as he was on the Sicilian bench in four different spells.
Both tacticians are forced to make changes, as Palermo have Nicolas Bertolo and Ezequiel Munoz suspended, while Matias Silvestre and Armin Bacinovic are injured.
Fabrizio Miccoli returns from his ban to boost the attack with Abel Hernandez.
Udinese’s banned list includes Antonio Floro Flores, Diego Fabbrini and Maurizio Domizzi, on top of injured Mehdi Benatia, Damiano Ferronetti, Emmanuel Badu and Mauricio Isla.
Di Natale hopes to close in on Capocannoniere Zlatan Ibrahimovic and is supported by Almen Abdi. Dusan Basta passes a fitness test to make his comeback after a month on the sidelines.
Palermo: 1 Viviano, 18 Labrin, 15 Milanovic, 2 Mantovani; 31 Pisano, 8 Migliaccio, 23 Donati, 5 Barreto, 42 Balzaretti; 11 Hernandez, 10 Miccoli
Palermo bench: 33 Tzorvas, 13 Aguirregaray, 20 Acquah, 7 Della Rocca, 17 Vazquez, 27 Ilicic, 19 Budan
Udinese: 1 Handanovic, 16 Coda, 5 Danilo, 24 Ekstrand; 8 Basta, 66 Pinzi, 4 Pazienza, 20 Asamoah, 26 Pasquale; 23 Abdi; 10 Di Natale
Udinese bench: 21 Padelli, 13 Neuton, 37 Pereyra, 6 Fernandes, 92 Vydra, 27 Armero, 25 Torje
Think you know your Italian football? Share your knowledge, tips and comments to win cash prizes in OLBG's World Cup tipster competition  - £10,000 to be won!