Parma will have to survive the drop without the services of McDonald Mariga for the rest of the campaign.
The Kenyan limped out of the 2-0 win over Novara on Wednesday with an injury which has proved to be serious.
The 25-year-old has damaged ligaments in his right knee which will keep him out of action until next season.
Mariga joined Parma in January from Spanish side Real Sociedad. He has scored one goal in 11 Serie A games since.
The player is actually owned by Inter and Parma have an option to sign a 50 per cent share in him at the end of the season.