Roma try to keep European hopes alive against Vincenzo Montella’s Catania, while Lecce face a new Fiorentina Coach in a relegation dogfight.
The action continues on Sunday with the Champions League and Scudetto still in the balance, including the huge Milan derby.
Click here  for all the individual match previews.
Think you know your Italian football? Share your knowledge, tips and comments to win cash prizes in OLBG's tipster competition  - £11,000 to be won monthly!