There are reports this could be the final game for Lecce Coach Gigi De Canio, as a former Inter legend is ready to take over.
De Canio had already offered his resignation earlier this season, but it was rejected by the club.
Recent results have not improved and Thursday's shock 1-0 home defeat to local rivals Bari was a bitter blow.
It's rumoured defeat to Lazio today will spell the end of De Canio's reign at the Stadio Via del Mare.
Options to take over include Gigi Cagni and former Inter legend Beppe Bergomi.
It would be Bergomi's first management job, although he had also been linked with the Nerazzurri bench when Rafa Benitez departed.