Dejan Stankovic supports Samuel Eto'o and Diego Milito as Inter welcome Marco Di Vaio's Bologna.
These two sides were held in a stalemate when they met back in Week 1, so it is not necessarily an easy task for Leonardo's men.
Eto'o is fielded in his preferred more advanced position alongside Milito, as Stankovic takes the trequartista role in Wesley Sneijder's absence.
Bologna adopt a five-man midfield with Di Vaio as the lone centre-forward, although Gaston Ramirez, Diego Perez and Albin Ekdal can push up with more creative options.
So far in his Inter career, Leonardo has a 100 per cent record of three wins between Serie A and the Coppa Italia.
Inter: 12 Castellazzi, 13 Maicon, 6 Lucio, 2 Cordoba, 26 Chivu; 4 Zanetti, 19 Cambiasso, 8 Thiago Motta; 5 Stankovic; 9 Eto'o, 22 Milito
Inter bench: 21 Orlandoni, 15 Ranocchia, 17 Mariga, 23 Materazzi, 27 Pandev, 39 Santon, 88 Biabiany
Bologna: 1 Viviano; 8 Garics, 6 Britos, 13 Portanova, 19 Rubin; 10 Ramirez, 15 Perez, 26 Mudingayi, 7 Della Rocca; 12 Ekdal; 9 Di Vaio
Bologna bench: 22 Lupatelli, 16 Esposito, 17 Radovanovic, 20 Gimenez, 21 Cherubin, 24 Buscé, 32 Casarini