Inter revamp their tactics again for the Europa League trip to Partizan Belgrade, adopting a 4-5-1 system.
The Nerazzurri scraped a last-minute 1-0 victory over the Serbians last time out and now enter a passionate Belgrade atmosphere with kick-off at 20.00 GMT.
Andrea Stramaccioni is without the injured Andrea Ranocchia and Walter Samuel, adding to long-term absentees Wesley Sneijder, Dejan Stankovic, Cristian Chivu and Philippe Coutinho.
The emergency situation sees him adjust his tactics again for a 4-5-1 system with Marko Livaja the lone centre-forward.
The defence is revamped completely with Jonathan and Yuto Nagatomo around Matias Silvestre and Juan Jesus.
Partizan Belgrade are relying on starlet Lazar Markovic as part of a supporting trio for Scepovic rather than Aleksandar Mitrovic.
Partizan Belgrade: Petrovic; Miljkovic, Ostojic, Ivanov, Lazevski; Medo, Smiljanic; Tomic, S Ilic, L Markovic; S Scepovic
Partizan bench: R Ilic, Volkov, Sretenovic, Ninkovic, Jojic, M Scepovic, Mitrovic
Inter: Handanovic; Jonathan, Silvestre, Juan Jesus, Nagatomo; Zanetti, Mudingayi, Cambiasso, Guarin, Alvaro Pereira; Livaja
Inter bench: Castellazzi, Gargano, Pasa, Romano, Palacio, Milito, Cassano