Juventus rely on Fabio Quagliarella for tonight’s trip to Pescara, while Juan Fernando Quintero starts just days after fainting during training.
The Stadio Adriatico hosts the Serie A leaders at 19.45 GMT.
There was tension in the Bianconeri camp leading up to the game, as Paul Pogba was dropped as punishment for arriving late to two training sessions.
Simone Pepe and Paolo De Ceglie are also injured, while Mauricio Isla again steps in for Stefan Lichtsteiner.
Quagliarella starts with Sebastian Giovinco, as Mirko Vucinic is still not 100 per cent fit.
Pescara turned a corner last week by beating Parma 2-0 and hope to continue their surprisingly strong record against Juventus here.
Quintero is fit to start despite being rushed to hospital after fainting during a training session on Tuesday, reportedly due to an allergic reaction.
Giuseppe Colucci, Manuele Blasi, Alessandro Crescenzi, Christian Terlizzi and Luca Savelloni are sidelined.
Meanwhile, there was bad news for Juventus today as two of their Primavera youth players fractured their fibulas.
Joel Untersee – who has played with the senior squad over the summer – and Gabriel Appelt both suffered fractures to the fibula.
Pescara: Perin; Cosic, Bocchetti, Capuano; Zanon, Nielsen, Cascione, Quintero, Modesto; Abbruscato, Jonathas
Pescara bench: Pellizzoli, Balzano, Romagnoli, Soddimo, Bjarnason, Celik, Weiss, Caprari, Vukusic
Juventus: Buffon; Barzagli, Bonucci, Chiellini; Isla, Vidal, Pirlo, Marchisio, Asamoah; Giovinco, Quagliarella
Juventus bench: Storari, Rubinho, Lichtsteiner, Lucio, Caceres, Marrone, Padoin, Giaccherini, Vucinic, Bendtner, Matri