Miralem Pjanic will replace the suspended Daniele De Rossi as Roma host Torino at Stadio Olimpico.
Zdenek Zeman has opted to field the Bosnian midfielder in place of the inspirational vice-captain after his straight red card last weekend.
Elsewhere, Leandro Castan comes in for Nicolas Burdisso at centre-back, to pair Ivan Piris, Marquinhos and Federico Balzaretti.
Michael Bradley and Alessandro Florenzi play alongside Pjanic, whilst Francesco Totti, Erik Lamela and Pablo Osvlado start up front.
For Torino, Angelo Ogbonna comes in for Guillermo Rodriguez in defence, whilst Mario Santana and Alessandro Sgrigna start up top.
Roma: Goicoechea; Piris, Marquinhos, Castan, Balzaretti; Bradley, Pjanic, Florenzi; Lamela, Totti, Osvaldo
Torino: Gillet; D'Ambrosio, Ogbonna, Glik, Darmian; Basha, Gazzi; Cerci, Santana, Bianchi, Sgrigna