UEFA have opened disciplinary proceedings against Lazio and Tottenham Hotspur after incidents during their Europa League clash last November.
The Biancocelesti tifosi are alleged to have thrown missiles at the away fans inside the stadium and were also heard chanting racist abuse at the Spurs supporters.
Both sets of supporters were also seen targeting one another before the game in Rome itself.
A statement from the governing body read: "UEFA has opened disciplinary proceedings against S.S. Lazio. Charges relate to the alleged racist behaviour of Lazio supporters during the Italian club's 0-0 UEFA Europa League Group J draw against Tottenham Hotspur FC in Rome on 22 November 2012.
"Proceedings will also be instigated against S.S. Lazio for throwing of missiles and/or fireworks by their supporters, incidents of a non-sporting nature, late team arrival at the stadium, and late handling of the team sheet.
"UEFA will also commence proceedings against Tottenham Hotspur FC, who face charges related to crowd disturbances.
"These cases will be discussed by the UEFA Control and Disciplinary Body on 24 January 2013."