Parma are the only side with an unbeaten home record and they welcome leaders Juventus fresh from a shock defeat.
The Ducali have a remarkable run of results at the Stadio Tardini, winning six of their last nine in front of their own fans.
Yohan Benalouane and Alessandro Lucarelli are suspended, but Jaime Valdes returns from a one-match ban.
Amauri takes on his old teammates, partnered by youngster Ishak Belfodil.
Juventus were shocked 2-1 by 10-man Sampdoria last week and taken to extra time by Milan in the Coppa Italia quarter-final on Wednesday night, so fatigue could also be an issue.
Claudio Marchisio, Giorgio Chiellini, Simone Pepe and Nicklas Bendtner are injured with Kwadwo Asamoah on African Cup of Nations duty.
Sebastian Giovinco starts against his former club with Fabio Quagliarella, while Paul Pogba is given a chance in midfield.
There is a long-standing rivalry between these sides and reports of scuffles outside the stadium caused by Juventus ultras before the game.
Parma: Mirante; Zaccardo, Paletta, Santacroce; Biabiany, Marchionni, Valdes, Parolo, Gobbi; Amauri, Belfodil
Parma bench: Pavarini, De Angelis, Morrone, Palladino, Musacci, Acquah, Sansone, Fideleff, Ninis, Rosi, Pabon
Juventus: Buffon; Barzagli, Bonucci, Caceres; Lichtsteiner, Vidal, Pirlo, Pogba, Padoin; Giovinco, Quagliarella
Juventus bench: Storari, Branescu, Vucinic, De Ceglie, Peluso, Giaccherini, Matri, Isla, Beltrame, Marrone
Think you know your Italian football? Share your knowledge, tips and comments to win cash prizes in OLBG's tipster competition  - £11,000 to be won monthly!