Juventus have a completely revamped midfield as they welcome Udinese, but Antonio Di Natale is not fit to start.
The Bianconeri have picked up just one point from two rounds and saw their lead at the top of the table sliced to three points going into this weekend.
Antonio Conte has to completely reshuffle his midfield, missing Andrea Pirlo, Claudio Marchisio, Simone Pepe, Kwadwo Asamoah, Giorgio Chiellini and Nicklas Bendtner.
Paul Pogba steps in and Arturo Vidal is able to start despite an ankle problem, joining Emanuele Giaccherini, Stephan Lichtsteiner and Paolo De Ceglie.
Mirko Vucinic returns to the starting XI alongside Sebastian Giovinco.
Udinese are without Zeljko Brkic, Diego Fabbrini, Mehdi Benatia and Emmanuel Badu, while Di Natale was debilitated by flu this week and can only start from the bench.
Therefore, Roberto Pereyra is pushed into a more advanced role as support for Luis Muriel.
Snow is expected at the Juventus Stadium this evening, but miles of underground heating pipes should ensure the game goes ahead without problems.
Juventus: Buffon; Barzagli, Bonucci, Caceres; Lichtsteiner, Vidal, Pogba, Giaccherini, De Ceglie; Vucinic, Giovinco
Juventus bench: Storari, Rubinho, Peluso, Rugani, Garcia, Padoin, Marrone, Isla, Schiavone, Matri, Beltrame, Kabashi
Udinese: Padelli; Heurtaux, Domizzi, Danilo; Basta, Pinzi, Allan, Lazzari, Pasquale; Pereyra; Muriel
Udinese bench: Scuffet, Pawlowski, Coda, Angella, Faraoni, Silva, Merkel, Ranegie, Di Natale, Maicosuel, Campos, Fabbrini, Merkel