Angelo Palombo has not recovered in time for Sampdoria’s trip to Napoli on Sunday afternoon.
The captain, who spent most of his career in midfield and has been revitalised as a centre-back, is not even in the squad.
Eder has returned after he was given compassionate leave in Brazil last week.
Sampdoria squad for Napoli: Berni, Da Costa, Romero; Berardi, Castellini, Costa, De Silvestri, Gastaldello, Mustafi, Poulsen, Rodríguez, Rossini; Krsticic, Maresca, Munari, Obiang, Poli, Soriano; Eder, Estigarribia, Icardi, Maxi Lopez, Sansone
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