Lazio will start with Sergio Floccari as the lone front-man when they face Pescara at Stadio Olimpico this evening.
The 31-year-old will play up front in place of the injured Miroslav Klose, whilst new signing Louis Saha remains on the bench.
For Pescara meanwhile, they drop young goalkeeper Mattia Perin in favour of Ivan Pelizzoli.
Lazio: Marchetti; Konko, Cana, Dias, Radu; Candreva, Gonzalez, Ledesma, Hernanes, Lulic; Floccari
Pescara: Pelizzoli; Balzano, Cosic, Bocchetti, Capuano, Zauri; Rizzo, Cascione, Bjarnason; Abbruscato, Celik