Atalanta and Bologna are not mathematically safe yet and go head-to-head for that final push over the edge.
The action kicks off in Bergamo at 17.00 UK time (16.00 GMT), click here for a match preview .
The Orobici are decimated going into this game, as Giacomo Bonaventura and Lionel Scaloni join Cristiano Raimondi and Carlos Carmona on their bans.
Riccardo Cazzola, Franco Brienza, Guido Marilungo and Igor Budan are all injured.
Maxi Moralez takes a supporting role behind German Denis and Inter-owned striker Marko Livaja.
Bologna have Manolo Gabbiadini suspended and Niccolo Cherubin out for the rest of the season with a fractured foot.
Cristian Pasquato is therefore given the opportunity to shine with Panagiotis Kone and Alessandro Diamanti behind lone centre-forward Alberto Gilardino.
Atalanta: Consigli; Ferri, Stendardo, Lucchini, Del Grosso; Giorgi, Cigarini, Biondini, Moralez; Livaja, Denis
Bologna: Curci; Garics, Sorensen, Antonsson, Morleo; Perez, Taider; Kone, Diamanti, Pasquato; Gilardino
Think you know your Italian football? Share your knowledge, tips and comments to win cash prizes in OLBG's tipster competition  - £11,000 to be won monthly!