It’s a battle for the Capocannoniere crown, as Udinese’s Antonio Di Natale takes on Giuseppe Rossi and Fiorentina.
It kicks off at the Stadio Friuli at 14.00 GMT, click here for a match preview .
Rossi is currently top scorer in Serie A with 11 goals in 12 games and leads the way for the Viola as they continue their march on European places.
He is joined by Juan Guillermo Cuadrado – who is still co-owned by Udinese – and Joaquin, while David Pizarro is also familiar with the Friuli turf. Mario Gomez is still unavailable.
Udinese have Di Natale back from injury and he provides a massive boost to their capabilities, though Matias Ranegie and Nico Lopez miss out.
Luis Muriel was on international duty with Colombia, so Francesco Guidolin considers him to be fit only for the bench.
Curiously, these teams have not shared the spoils since January 2006, earning seven wins each home and away.
Fiorentina do not have a good record at the Stadio Friuli, losing six of their last seven visits.
Udinese: Brkic; Hertaux, Danilo, Domizzi, Gabriel Silva; Pinzi, Lazzari; Basta, Pereyra, Fernandes; Di Natale
Udinese bench: Kelava, Allan, Edinaldo, Bubnac, Badu, Muriel, Alves, Douglas, Widmer, Merkel, Maicosuel, Zielinski
Fiorentina: Neto; Tomovic, Rodriguez, Savic, Pasqual; Aquilani, Pizarro, Borja Valero; Joaquin, Rossi, Cuadrado
Fiorentina bench: Munua, Alonso, Roncaglia, Compper, Rebic, Fernandez, Vecino, Ambrosini, Wolski, Matos, Vargas, Ilicic
Think you know your Italian football? Share your knowledge, tips and comments to win cash prizes in OLBG's World Cup tipster competition  - £10,000 to be won!