Tonight Juventus and Inter renew their bitter rivalry, but first Roma host Parma and Napoli face a tricky Atalanta test.
Click here for match previews from every single Serie A Week 22 encounter , plus reports of Saturday’s games Cagliari-Fiorentina, Bologna-Udinese and Milan-Torino.
There is no brunchtime match today, as Genoa-Sampdoria was moved to Monday evening.
At 14.00 GMT Roma hope to close the gap further at the top of the table, but have to get past Antonio Cassano’s on-form Parma.
Napoli need to stop dropping points and visit Atalanta, while Lazio take on Chievo and Alberto Malesani makes his Sassuolo debut against Verona.
Catania-Livorno is a desperate bottom of the table dogfight.
Think you know your Italian football? Share your knowledge, tips and comments to win cash prizes in OLBG's tipster competition  - £11,000 to be won monthly!