Juventus host Chievo and tonight Roma face on-form Sampdoria, while Napoli look for Sassuolo revenge and Lazio visit Catania.
Click here for match previews from every single Serie A Week 24 tie , plus reports from Milan-Bologna and Fiorentina-Inter.
It all begins today at 11.30 GMT when Edy Reja defends his unbeaten Serie A run on the Lazio bench against bottom of the table Catania, who bring an air of desperation to their game.
This afternoon leaders Juventus take on the Flying Donkeys, Napoli want to make up for their earlier draw with Sassuolo and Atalanta-Parma is a duel for European ambitions.
Genoa-Udinese and Cagliari-Livorno are intriguing relegation battles.
At 19.45 GMT Roma aim to keep their Scudetto hopes alive and recover from the Coppa Italia thrashing by taking on fiery Sampdoria.
On Monday evening the round concludes with Verona against Torino, a head-to-head of the surprise high-flyers.