Mauro Zarate starts for Lazio despite his row with Edy Reja, as they welcome Napoli to the Stadio Olimpico.
The lunchtime kick-off is at 12.30 local time, 11.30 in the UK, and sees the former leaders eager to get back on track after two consecutive defeats.
The Biancocelesti rested Hernanes for the midweek 1-0 loss at Cesena and he returns to the midfield.
Zarate is in the starting XI despite his row with Coach Reja that had fuelled reports of a January sale, so Tommaso Rocchi is again on the bench.
Napoli are without the injured Andrea Dossena and Salvatore Aronica, while Walter Gargano is suspended.
Michele Pazienza and Hugo Campagnaro are not 100 per cent fit, but still start.
Juan Zuniga was expected to step in for Dossena, but instead the role has gone to Luigi Vitale.
Lazio: Muslera; Lichtsteiner, Biava, Dias, Radu; Brocchi, Ledesma; Mauri, Hernanes, Zarate; Floccari
Lazio bench: Berni, Diakitè, Garrido, Matuzalem, Bresciano, Foggia, Rocchi
Napoli: De Sanctis; Grava, Cannavaro, Campagnaro; Maggio, Pazienza, Yebda, Vitale; Hamsik, Lavezzi; Cavani
Napoli bench: Iezzo, Santacroce, Cribari, Blasi, Zuniga, Dumitru, Sosa