Roma take on their Cagliari taboo and Napoli visit Antonio Cassano’s Parma, while Milan have a difficult trip to Genoa.
Click here for individual match previews for every single Serie A Week 32 tie , plus reports from Saturday’s Verona Derby and Inter-Bologna.
The action kicks off today at 11.30 UK time (10.30 GMT) with Lazio hosting Sampdoria to keep their European dreams alive.
At 14.00 UK time Roma try to close the gap further on leaders Juventus, but face a tricky trip to Cagliari, where they haven’t won for 19 years.
Fiorentina take on Udinese, Atalanta try for a seventh straight win against Sassuolo and Catania are at the Last Chance Saloon with Torino.
At 19.45 UK time there’s an intriguing battle for Europe as a revitalised Napoli visit Cassano’s Parma.
The round concludes on Monday when Juventus host Livorno at 18.00 UK time and Milan travel to Alberto Gilardino’s Genoa at 20.00.