Juventus celebrate their Scudetto and against Cagliari have the chance to become the first team ever to go over 100 Serie A points.
It kicks off at 14.00 UK time (13.00 GMT), click here for a match preview .
This game will be followed by the presentation of the Serie A trophy and an open top bus celebratory parade through the streets of Turin.
Antonio Conte’s men have already shattered numerous records and beat Inter’s 2006-07 tally of 97 points.
Against Cagliari today they can go up to 102, becoming the first club ever to reach triple figures in this tournament.
The Bianconeri can also end the season with a 100 per cent home record.
Giorgio Chiellini begins his three-match ban after he was caught on camera lashing out an elbow at Miralem Pjanic, while Arturo Vidal and Mirko Vucinic are injured.
Cagliari have already secured their Serie A status some weeks ago and come to Turin without Vlada Avramov, Eros Pisano, Matias Cabrera, Albin Ekdal, Nene, Matias Vecino and Nicola Murru.
Juventus: Buffon; Caceres, Bonucci, Ogbonna; Lichtsteiner, Pogba, Pirlo, Marchisio, Asamoah; Tevez, Llorente
Cagliari: Silvestri; Astori, Perico, Rossettini, Avelar; Conti, Tabanelli, Dessena; Cossu; Pinilla, Ibarbo
Think you know your Italian football? Share your knowledge, tips and comments to win cash prizes in OLBG's tipster competition  - £11,000 to be won monthly!