Milan could book their spot in the next round of the Europa League as they host Austria Vienna with Andre Silva and Patrick Cutrone in attack.
It kicks off at San Siro at 20.05 GMT.
Vincenzo Montella’s side are on the verge of European progress, even if their Serie A form is faltering.
Suso, Alessio Romagnoli, Ignazio Abate and Andrea Conti are on the treatment table, but Hakan Calhanoglu returns after missing Saturday’s 2-1 defeat to Napoli.
Andre Silva scored a hat-trick when Milan won 5-1 away to Austria Vienna in September and he leads the way with teenage hitman Cutrone.
Milan will be through to the next round if they win, while a draw would also be enough if Rijeka fail to conquer AEK Athens.
Austria Vienna need a victory and must hope AEK don’t get all three points.
Milan: G Donnarumma; Musacchio, Bonucci, Zapata; Borini, Biglia, Calhanoglu, Kessie, Rodriguez; Silva, Cutrone
Milan bench: Storari, Bonaventura, Kalinic, Gomez, Montolivo, Antonelli, Locatelli
Austria Vienna: Pentz; De Paula, Borkovic, Mohammed, Salamon; Serbest, Holzhauser; Prokop, Abdullahi, Pires; Monschein
Austria Vienna bench: Hadzikic, Gluhakovic, Tajouri-Shradi, Friesenbicher, Blauensteiner, Lee, Sarkaria
Ref: Treimanis (LTA)
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