Atalanta, Milan and Lazio are top seeds in the Europa League Round of 32 draw, but Napoli risk a much tougher fixture.
The Partenopei drop down into the competition after finishing third in their Champions League group behind Manchester City and Shakhtar Donetsk.
Due to the co-efficient, Napoli will not be top seeds in the draw on Monday and run the risk of a very tricky opponent.
The most dangerous options are Arsenal, Atletico Madrid and Zenit, but Villarreal, Sporting CP and CSKA Moscow are not to be underestimated either.
Milan, Lazio and Atalanta are top seeds and will therefore also play the first leg away from home.
Potential opponents they won’t want to be drawn against include Borussia Dortmund – who also drop down from the Champions League – AEK Athens Spartak Moscow, Olympique Marseille, Real Sociedad and Celtic.
Atalanta can’t face Olympique Lyonnais, having already beaten them in the group phase, but Milan and Lazio could be drawn with them.
Top seeds: CSKA Moscow, RB Leipzig, Atletico Madrid, Sporting CP, Villarreal, Dinamo Kiev, Sporting Braga, Lokomotiv Moscow, Viktoria Plzen, Arsenal, RB Salzburg, Athletic Bilbao, Zenit, Milan, Atalanta, Lazio
Second seeds: Spartak Moscow, Celtic, Borussia Dortmund, Napoli, Astana, Partizan Belgrade, Ludogorets, AEK Athens, Lyon, Copenhagen, Steaua Bucharest, Red Star Belgrade, Olympique Marseille, Ostersunds, Nice, Real Sociedad