Yann Karamoh gets his chance from the start, as Luciano Spalletti names a rotated Inter team for the Coppa Italia tie with Pordenone.
The Coach confirmed yesterday that he would be making changes, with chances for the likes of the young Frenchman, Andrea Ranocchia and backup goalkeeper Daniele Padelli.
Spalletti has been as good as his word, with only Milan Skriniar and Matias Vecino remaining in the starting XI after the 0-0 draw with Juventus on Saturday.
Andrea Pinamonti starts with Karamoh in attack, with the youngsters joined by Italian international Eder.
Joao Cancelo also gets his first start, with the full-back appearing to be playing on the right wing in a 4-2-3-1 system.
The Lega Pro visitors have gone for a 4-3-2-1, with Simone Magnaghi leading the line.
The winner of this match will face either Milan or Verona in the quarter-finals.
Inter: Padelli; Nagatomo, Skriniar, Ranocchia, Dalbert; Vecino, Gagliardini; Cancelo, Eder, Karamoh; Pinamonti
Inter bench: Handanovic, Berni, Lombardoni, Santon, Borja Valero, Emmers, Brozovic, Candreva, Perisic, Icardi
Pordenone: Perilli; Formiconi, Stefani, Bassoli, Nunzella; Misuraca, Burrai, Lulli; Maza, Berrettoni; Magnaghi
Pordenone bench: Zommers, De Agostini, Parodi, Buratto, Pellegrini, Visentin, Ciurria, Raffini, Martignago, Silvestro, Danza, Toffolini