Lazio have Ciro Immobile back in the starting XI with Sergej Milinkovic-Savic, but host a Crotone side fresh from their first win under Walter Zenga.
It kicks off at 11.30 GMT, follow the build-up and action from all today’s Serie A games on the LIVEBLOG.
The Aquile have run into some problems lately, suffering a 3-1 home defeat to Torino in which Immobile was sent off and then pegged back in a 3-3 thriller by Atalanta.
Immobile has now completed his ban and is ready to lead the attack with support from Luis Alberto and Paris Saint-Germain transfer target Milinkovic-Savic.
Luis Nani has shaken off a muscular problem and Felipe Anderson can give an injection of pace off the bench.
Crotone are fresh from their first win under new Coach Zenga, having beaten Chievo 1-0 last weekend.
It has been a rough time for the Calabrese club, as Davide Nicola masterminded their comeback to secure Serie A safety last season and walked away in protest after the President undermined him by entering the locker room at half-time.
There’s a hefty injury list ruling out Mariano Izco, Andrea Nalini, Stefan Simic and Marco Tumminello.
Marcello Trotta, Ante Budimir and Adrian Stoian form the trident attack.
Lazio: Strakosha; Patric, De Vrij, Wallace; Marusic, Murgia, Parolo, Lukaku; Luis Alberto, Milinkovic-Savic; Immobile
Crotone: Cordaz; Sampirisi, Ajeti, Ceccherini, Martella; Rohden, Barberis, Mandragora; Trotta, Budimir, Stoian