Gregoire Defrel is out injured against his former club, as Roma host Sassuolo, but Patrik Schick will be in the starting XI.
It kicks off on Saturday at 14.00 GMT, click here for a match preview.
The Giallorossi are without Defrel, who picked up a thigh problem in training, and long-term absentee Rick Karsdorp.
It is still a reunion for other ex-Sassuolo men Lorenzo Pellegrini and Coach Eusebio Di Francesco.
In his Press conference today, Di Francesco confirmed striker Schick will start the game.
Roma squad for Sassuolo: Alisson Becker, Skorupski, Lobont; Juan Jesus, Kolarov, Moreno, Fazio, Bruno Peres, Emerson Palmieri, Manolas; Nainggolan, Strootman, Pellegrini, De Rossi, Gonalons, Florenzi, Gerson; Perotti, Dzeko, Schick, Cengiz Under, Antonucci, El Shaarawy