Milan have Gianluigi Donnarumma back with teenage hitman Patrick Cutrone, but Fiorentina surprisingly bench Federico Chiesa.
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Gennaro Gattuso’s Rossoneri coaching career got off to a dismal start, but there was a single ray of hope on Wednesday when knocking rivals Inter out of the Coppa Italia Quarter-Final in extra time.
Cutrone got the only goal of the game, making him Milan’s top scorer in all competition this season with nine.
The 19-year-old has leapfrogged Andre Silva and even Nikola Kalinic in the pecking order, especially as the Croatia international went off with an ankle problem in that Inter match and is left at home.
Suso and Fabio Borini flank Cutrone, with Jack Bonaventura pushed back into midfield.
Antonio Donnarumma – Gigio’s older brother – was rushed in to start against Inter after both Gianluigi and Marco Storari pulled out with muscular problems, but the teenager is back for his 100th appearance in a Milan jersey.
Fiorentina were also in the Coppa Italia on Tuesday, unable to overturn an early Senad Lulic goal as they crashed out away to Lazio.
Coach Stefano Pioli rested several players for that game, including German Pezzella, Marco Sportiello, Giovanni Simeone and Cyril Thereau.
They all return, but Federico Chiesa is unexpectedly left on the bench.
Pioli has only beaten Milan twice in his managerial career with both wins being three days apart (24-27 January 2015).
The Rossoneri haven’t conquered the Stadio Franchi since a 2-0 result in March 2014, followed by two defeats and a 0-0 draw.
Fiorentina: Sportiello; Laurini, Astori, Pezzella, Biraghi; Badelj, Veretout; Gil Dias, Benassi, Thereau; Simeone
Milan: G Donnarumma; Calabria, Romagnoli, Bonucci, Rodriguez; Kessie, Montolivo, Bonaventura; Suso, Cutrone, Borini