Ciro Immobile is expected to only be on the bench when Lazio visit Milan on Sunday evening due to injury.
It kicks off at San Siro on Sunday at 17.00 GMT, click here for a match preview.
Immobile is the Capocannoniere of Serie A with 20 goals, but he limped off during last week’s 5-1 victory over Chievo.
He missed Wednesday’s rescheduled tie with Udinese, a 3-0 win, and should be back in the squad for this weekend.
However, Immobile skipped this morning’s training session and is therefore expected to be on the bench at best.
With Felipe Caicedo also sidelined, Felipe Anderson should take the centre-forward role with support from Luis Alberto.
Another alternative would be Luis Nani, who was on target midweek against Udinese.
Curiously, Milan and Lazio face off again next week in Tuesday’s Coppa Italia semi-final, first leg fixture.
See the latest Serie A predictions and betting tips with Eurotips.co.uk