Lazio went through a rough patch, but have found their form again and aim to take it out on sorry Sassuolo with Ciro Immobile and Felipe Anderson.
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Simone Inzaghi’s side are having a fantastic season, as they crushed FC Steaua Bucharest 5-1 on Thursday to set up a Europa League Round of 16 clash with Dinamo Kiev.
This coming Wednesday, they’ll go head-to-head with Milan at the Olimpico in the second leg of the Coppa Italia semi-final.
A win here would also consolidate third place in Serie A, but there’s the issue of all these games taking a toll on resources and the need for squad rotation.
Despite that, they start essentially a full strength XI with Sergej Milinkovic-Savic, Felipe Anderson and Ciro Immobile.
Contract rebel Stefan de Vrij, Marco Parolo and Luis Alberto are rested.
Beppe Iachini had such a strong start with the Neroverdi, but it seems to have evaporated in a seven-round winless streak that left them five points above the relegation zone.
Edoardo Goldaniga sits out a ban with injured Alessandro Matri and Timo Letschert.
Pol Lirola, Matteo Politano, Khouma Babacar and Francesco Magnanelli are all carrying little niggling injuries.
When these sides met at the Stadio Olimpico earlier this season, Sassuolo had taken the lead through a Domenico Berardi penalty only to be crushed 6-1.
Sassuolo: Consigli; Lirola, Adjapong, Acerbi, Peluso, Rogerio; Missiroli, Magnanelli, Mazzitelli; Berardi, Babacar, Politano
Sassuolo bench: Pegolo, Lemos, Dell'Orco, Sensi, Duncan, Cassata, Biondini, Pierini, Ragusa, Frattesi
Lazio: Strakosha; Wallace, Luiz Felipe, Radu; Marusic, Murgia, Leiva, Milinkovic-Savic, Lukaku; Felipe Anderson; Immobile
Lazio bench: Guerrieri, Vargic, Patric, Basta, Bastos, Caceres, De Vrij, Lulic, Parolo, Nani, Luis Alberto, Caicedo
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