Join us for all the build-up and action from SPAL-Bologna, Lazio-Juventus between second and third and the Derby del Sole Napoli-Roma.
We begin at 14.00 GMT at the Stadio Mazza in Ferrara, where SPAL host local rivals Bologna in their desperate search for survival in the top flight.
At 17.00 GMT, Lazio are out for another spectacular scalp, having already beaten Juventus twice this season in Serie A and the Italian Super Cup.
Ciro Immobile and co were the first team to conquer the Juventus Stadium in 57 top flight matches.
At 19.45 GMT, it’s another Super Saturday showdown at the Stadio San Paolo, where leaders Napoli welcome stuttering Roma and seek a record-breaking 11th straight Serie A victory.
There’s some of Italy’s most exciting talent on show today, from Immobile and Sergej Milinkovic-Savic to Paulo Dybala, from Dries Mertens to Cengiz Under.
See the latest Serie A predictions and betting tips with Eurotips.co.uk