Genoa and Cagliari are not clear from the threat of relegation and must go all out to avoid being sucked into the danger zone.
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The race to avoid the drop is getting closer than expected, as SPAL beat Bologna yesterday for their second straight win and are making the sides above them a little nervous.
That includes both these clubs, although Genoa have enjoyed a recent upturn in fortunes with three consecutive victories including a win over Inter.
This run ground to a halt with their 2-0 defeat to Bologna and injuries are starting to take their toll, missing Miguel Veloso, Giuseppe Rossi, Armando Izzo and Adel Taarabt.
Goran Pandev hopes to continue his very impressive form in attack with Andrej Galabinov rather than Gianluca Lapadula.
Cagliari must do without midfielder Luca Cigarini and forward Diego Farias, so North Korean striker Han Kwong-Sang again gets a chance with ex-Genoa hero Leonardo Pavoletti.
The Sardinians need to regain some confidence after their 5-0 hammering at the hands of Napoli.
The last time this fixture ended in a draw was 3-3 in Serie B in May 2002, followed by seven home wins and two for the Sardinians.
Both teams have found the net in seven of their last eight meetings, home and away. Cagliari kept just one clean sheet in their 30 trips to Marassi.
Genoa: Perin; Biraschi, Spolli, Zukanovic; Lazovic, Bertolacci, Hiljemark, Laxalt; Pandev, Galabinov
Cagliari: Cragno; Romagna, Ceppitelli, Castan; Faragò, Ionita, Barella, Joao Pedro, Lykogiannis; Han, Pavoletti
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