Milan need to pour all their focus on to Serie A and host a Chievo side in utter crisis, relying on Patrick Cutrone and Suso.
It kicks off at 14.00 GMT, follow the build-up and action from all today’s Serie A games on the LIVEBLOG.
The Rossoneri are out of the Europa League after their double defeat to Arsenal and need a boost to climb into the European places in Serie A.
Nikola Kalinic was dropped after showing a bad attitude in training, while Davide Calabria, Alessio Romagnoli and Ignazio Abate are injured.
Andrea Conti is on the bench for the first time in six months after his anterior cruciate ligament surgery.
Chievo miss Alessandro Gamberini and Riccardo Meggiorini, but opt for Mariusz Stepinski as the partner for Roberto Inglese, backed by Emanuele Giaccherini.
Rolando Maran is hanging by a thread after a disastrous run of results, culminating in third consecutive defeat to rivals Hellas Verona.
Chievo have beaten Milan only twice in 31 Serie A meetings, both at the Bentegodi in October 2002 and December 2005, along with six draws.
Milan: Donnarumma; Borini, Bonucci, Zapata, Rodriguez; Kessie, Biglia, Bonaventura; Suso, Cutrone, Calhanoglu
Chievo: Sorrentino; Jaroszynski, Bani, Tomovic, Cacciatore; Depaoli, Radovanovic, Castro; Giaccherini; Inglese, Stepinski
See the latest Serie A predictions and betting tips with Eurotips.co.uk