Diego Perotti and Gregoire Defrel are out of the Rome Derby, while Kostas Manolas and Alessandro Florenzi need fitness tests.
It kicks off on Sunday at 19.45 UK time (18.45 GMT), click here for a match preview.
Coach Eusebio Di Francesco confirmed in today’s Press conference that Defrel and Perotti would not be able to recover in time for this match with their arch rivals Lazio.
Manolas and Florenzi skipped training yesterday after suffering from flu symptoms.
It’s reported that while the centre-back is already well on the road to recovery, Florenzi remains in doubt.
Roma squad for Lazio: Alisson, Lobont, Skorupski; Luca Pellegrini, Juan Jesus, Kolarov, Capradossi, Fazio, Florenzi, Peres, Silva, Manolas; Nainggolan, Strootman, Lorenzo Pellegrini, De Rossi, Gonalons, Gerson; Dzeko, Schick, Under, Antonucci, El Shaarawy
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